ANTI OXIDANT LEVEL IN PATIENTS WITH MYOCARDIAL INFARCTION BY USING FRAP METHOD

Abstract

Cardiac diseases are the major cause of death especially Ischemic coronary Heart Disease (IHD) of the modern world. In our study the high level of serum in total cholesterol, low density lipoprotein, triglycerides were high and the levels of high density lipoprotein were observed. The mean ±SD levels of the cholesterol in patients were 225.19±49.69 mg/dl, triglyceride 189.73±73.21 mg/dl, LDL 132.42±31.12 (mg/dl) respectively. While the serum HDL was low as 36.16±5.04 (mg/dl) as compared with the normal level. Moreover ± SD of vitamin C levels in IHD patients were 333.79±64.19 (μmol/l), vitamin E levels were estimated as 368.14±70.8 (μmol/l), While Glutathione reduced (GSH) reported was 1840.9±354.05 (μmol/l). The study therefore highlights the value of serum antioxidants level in tissue injury due to oxidative stress in daily investigation along with other laboratory tests. The study was conducted in Faculty of Pharmacy during the year 2007-08.