INNOVATIVE TRANSDERMAL DRUG DELIVERY SYSTEMS & TECHNOLOGIES

Abstract

Transdermal drug delivery represents one of the most rapidly advancing areas of novel drug delivery. It has attracted researchers due to many biomedical advantages associated with it. However, excellent impervious nature of skin is the greatest challenge that has to be overcome for successfully delivering drug molecules to the systemic circulation by this route. Various formulation approaches and technological innovations used in designing delivery systems for maximizing percutaneous drug permeation have played important role in improving functionality of transdermal drug delivery systems and many more are expected to be seen in future. In this review, we would focus on the latest trends and developments, with futuristic perspective, over the transdermal drug delivery techniques, with special emphasis on the 2nd & third generation delivery systems. We would analyses the current status of the transdermal drug delivery, evaluating its therapeutic uses, its market share and the positioning of leading technologies. The pipeline of transdermal drugs is assessed by therapeutic indication and innovative delivery technologies are discussed at length and benchmarked against one another. The review also provides an in-depth analysis of the potential market for transdermal and transmucosal drug delivery.